Inception of Stratified Medicine
نویسندگان
چکیده
The art of predicting the results of any drug treatment has always been a topic of interest among the scientific community across the globe. Many diseases have been attributed to gene defects, giving rise to a whole new field of pharmacogenomics within the domain of clinical pharmacology. Stratified medicine is the science of associating such diseases with genetic defects and predicting the efficacy or toxicity of a particular drug treatment. The article provides an overview of how stratified medicine got evolved and its current and future clinical implications. It also explains how “companion diagnostics” play a crucial role in the success of stratified medicine along with its complex economics, pricing and reimbursement issues.
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